Comparism of Glycated Haemoglobin and OGTT Protocol in Diagnosis of Gestational Diabetes Mellitus in Northern Nigeria one of the 50 books to read published by at 2017 recommended for you if you want book about . one of the 50 books to read authored by Muazu Salisu, with page thickness Pages. you can found description at the bottom
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Abstract titletComparism of Glycated Haemoglobin and OGTT protocol in Diagnosis of Gestational Diabetes Mellitus in Northern NigeriaCo-authorstS. Muazu1, A. Tajudeen2, H. Bako3, M.B. Ahmad4.1Ahmadu Bello University, Internal Medicine, Zaria, Nigeria.2Rasheed Shekoni Specialist Hospital, Obstetrics and Gynaecology, Dutse, Nigeria.3Rasheed Shekoni Specialist Hospital, Chemical pathology, Dutse- Jigawa state, Nigeria.4Bayero University Kano, Chemical pathology, Kano, Nigeria.Abstract bodytBackgroundGestational diabetes mellitus is any degree of glucose intolerance that occurs for the first time in a pregnant woman with complete resolution after delivery. Most women with GDM revert to normal glucose metabolism after delivery however, there is a risk of developing type 2 diabetes later in life as are their children. The diagnosis of GDM requires determination of both fasting and post prandial blood glucose in an OGGT protocol. This method is resource consuming, inconvenient and cumbersome as such the need to devise or develop a new simple and effective technique.AimThe aim of this study is to determining the prevalence and find out if glycated haemoglobin determination can be used to diagnose GDM in this community.MethodsThe survey was conducted in an antenatal outpatient clinic within secondary health facility in north western Nigeria. It involved 174 pregnant non diabetic consenting women selected consecutively as they register with the clinic. They are mostly from the rural areas and are peasants or housewives at their third trimester of pregnancy. Ethical approval was sought and approved by the Ethics committee of the hospital.A detailed history was sought and documented. Physicals conducted, the weight, height, blood pressure and fundal height were determined.During next visit subjects were instructed to fast and venous blood was taken to determine FBG. Immediately a 75mg glucose anhydrous was administered to the subjects and blood glucose determine at one hour and two hours (OGGT method). Thereafter HBA1c was measured using a point of care Glover A1c metre Modified WHO criteria (2003) for diagnosis of GDM; FBG 5.1-7.0 with either 1 hour blood glucose u2265 10.0 or 2 hours blood glucose 8.5-11.0 following OGTT or HbA1c value of 5.7-6.5% was used.SPPS 23 was used to analysed the data with p value at 0.05ResultsA total of 174 pregnant women at third trimester were screened with means for age, gestational age and parity 24.5u00b16.5 years, 23u00b14.3 weeks and 3.0u00b12.0 respectively. Prevalence of gestational diabetes was found to be 10.3% (18/174) using the fasting and 2 hour post OGTT glucose. Only 4.6% or (8/174) subjects of those diagnosed turn out to be GDM with HbA1c testing.The means of age, parity, last child birth, PCV, total cholesterol and HDL were lower in GDM group than in normal group p0.05.The duration of last child birth 1.2u00b11.1 years in GDM was shorter than in normal group 1.9u00b11.4 years while HbA1c was higher 5.3u00b10.6% p0.05.Regression analysis showed shorter duration of last childbirth and increasing HbA1c as predictors of GDM, chi2 1.0 p
Comparism of Glycated Haemoglobin and OGTT Protocol in Diagnosis of Gestational Diabetes Mellitus in Northern Nigeria
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